Comparative study of three different coronaviruses: SARS, MERS, and COVID-19. Netra P. Neupane, Aman K. Das Department of Pharmaceutical Sciences, Sam Higginbottom University of Agriculture, Technology and Sciences, Prayagraj, U.P., India, 211007 Abstract: Coronavirus is enveloped, non-segmented, single-stranded, positive-sense RNA viruses. The novel coronavirus (2019-nCoV) has been declared a pandemic by the World Health Organization on 11 th March 2020. Accessing lots of literature and research paper we reviewed origin, history, genomics and epidemiology of SARS, MERS and COVID-19. The genomics of COVID-19 partially resembled that of SARS and MERS indicating a common origin from the bat. All three viruses possess specific accessory proteins as a distinctive feature. These coronaviruses have a different incubation period, basic reproduction number (R0), accessory proteins, case fatality ratio, etc. These human coronaviruses have similarity in terms of causing respiratory ...